Tuesday, 5 July 2016

Gliomas adapting to using fats for energy?

Brain tumours adapting to fats? The papers at the bottom of this page will go some way to allay any fears you may have. It underlines my approach of balancing out my fatty acids and testing through http://www.omegaquant.com/ every 3-6 months to examine my fatty acid profile via a blood sample. If you have brain cancer I believe this is the most important test you can have. 

The ratio of omega 3 and 6 is of vital importance. This is more important than simply monitoring ketosis and it compliments ketogenesis nicely. Brains want lots of DHA, especially brain afflicted with any kind of neurogenerate be disease. 

'The fatty acid composition of human gliomas differs from that found in non-malignant brain tissue.'

I actually touched on this in more depth in a January post. Brain cancer doesn't like DHA. Please read the whole post and bullet points to fully understand this.: 

The study I am currently critically analysing and has gained so much attention is this one below. I feel many people have been mislead by the findings so I will attempt to clear this up. 

I think it's a great study as it validates my approach, but I don't agree that all fats are created equal. This study analysed linoleic acid in vivo. The results were interesting to me, but not particularly surprising. I don't agree with the title or conclusions because I don't agree that all fats are created equal, the type and ratio are of critical importance. I completely agree that this is true under the conditions applied in the study. I really like the study, I just don't value the irresponsible conclusions made by journalists. I have access to the full study but this is the abstract:

Fatty acid oxidation is required for the respiration and proliferation of malignant glioma cells-


  1. The focus of the research team is unclear to me. The abstract said "the drug...", indicating to me that they have a pharmaceutical lean. Keep going. Info is power.

    1. its unclear to me too, they used linoleic acid, big fail when you take into account the fatty acid composition of glioma tissue and in brains of those with neurodegenerative disease. DHA has the opposite effect. The drug is potentially interesting but needs more research. The claims these researchers make and the conclusions they jump too are deeply concerning to me. You cannot make definitive claims about fatty acid metabolism of these cells when you are only testing linoleic acid.